Gastrointestinal

Nail Infection

Wound Infection

Detailed Description of PCR Tests Offered by Medex Laboratories Inc.

Polymerase Chain Reaction (PCR) testing is a highly sensitive and specific molecular diagnostic method used to detect the presence of pathogens by amplifying their DNA or RNA. Below is a breakdown of the different PCR tests offered by Medex Laboratories Inc. based on the requisition forms.

Urinary Tract Infection (UTI) PCR Test

What is a UTI?

A Urinary Tract Infection (UTI) occurs when bacteria, viruses, or fungi infect any part of the urinary system, including the bladder, kidneys, ureters, and urethra. UTIs are one of the most common infections and can cause discomfort, pain, and potential complications if left untreated.

Common Symptoms of a UTI:

✅ Frequent urge to urinate
✅ Burning sensation during urination
✅ Cloudy, bloody, or strong-smelling urine
✅ Pelvic pain or lower abdominal discomfort
✅ Fever or chills (sign of kidney infection)

What is the UTI PCR Test?

A UTI PCR (Polymerase Chain Reaction) Test is an advanced molecular diagnostic test that detects and identifies bacterial, viral, and fungal pathogens in the urinary tract. Unlike traditional urine cultures that take several days, PCR testing provides fast and highly accurate results within 24-48 hours.

Key Advantages of the UTI PCR Test:

🔬 Highly Accurate: Detects multiple pathogens with over 99% sensitivity and specificity
Rapid Results: Provides results within 24-48 hours, unlike culture tests that take 3-5 days
🦠 Detects Antibiotic Resistance Genes: Identifies resistance markers for personalized antibiotic treatment
Comprehensive Detection: Tests for multiple bacteria, fungi, and viruses in one sample

Who Should Get a UTI PCR Test?

The UTI PCR test is recommended for individuals experiencing:
Recurring or persistent UTIs despite treatment
Chronic urinary symptoms with negative urine cultures
Complicated UTIs in individuals with diabetes, pregnancy, or weakened immune systems
History of antibiotic resistance in previous infections

How is the UTI PCR Test Performed?

1️⃣  Sample Collection – A urine sample is collected using a clean-catch method at a lab or healthcare facility.
2️⃣  DNA/RNA Extraction – The sample is processed to extract genetic material from pathogens.
3️⃣  PCR Amplification & Analysis – The test amplifies microbial DNA, detecting UTI-causing pathogens.
4️⃣  Results Interpretation – A report is generated, identifying the exact bacteria, virus, or fungi responsible and any antibiotic resistance genes detected.

Pathogens Detected in UTI PCR Testing

Bacterial Infections:

  • Escherichia coli (E. coli) – The most common UTI-causing bacteria
  • Klebsiella pneumoniae
  • Enterococcus faecalis
  • Proteus mirabilis
  • Pseudomonas aeruginosa
  • Staphylococcus saprophyticus

Fungal & Viral Causes of UTI:

  • Candida species (Fungal UTIs)
  • Adenovirus (Viral UTIs)
  • BK Virus (BKV) – Common in kidney transplant patients

Why Choose PCR Over Traditional Urine Cultures?

Feature

PCR Test

Traditional Urine Culture

Detection Speed

24-48 hours

3-5 days

Sensitivity

Over 99% accuracy

Lower sensitivity

Antibiotic Resistance Detection

Yes

No

Multiple Pathogen Detection

Yes (bacteria, viruses, fungi)

Limited to bacterial growth

Interpreting Your Results

🔹 Positive Result – Confirms a UTI-causing organism; your doctor will prescribe targeted treatment.
🔹 Negative Result – No infection detected; alternative causes for symptoms should be evaluated.
🔹 Antibiotic Resistance Detected – Indicates which antibiotics may not be effective, guiding personalized treatment.

Next Steps After Testing

  • If an infection is detected, your doctor will prescribe an effective antibiotic based on resistance results.
  • Patients with frequent UTIs may require preventive strategies such as probiotics, dietary changes, and lifestyle modifications.
  • Additional testing may be needed for individuals with recurrent or complicated UTIs.

Insurance & Cost Coverage

Most insurance providers cover UTI PCR testing when medically necessary. Our team can assist with insurance verification and billing support.

Why Choose Our Lab for UTI PCR Testing?

Fast & Accurate Results – Detects infections within 24-48 hours
Comprehensive Pathogen Screening – Tests for bacteria, fungi, and viruses
Antibiotic Resistance Detection – Helps in targeted, effective treatment
CLIA-Certified & CAP-Accredited Lab – Ensuring high-quality testing standards
Expert Consultation Available – Helping patients and physicians interpret results

Sexually Transmitted Infection (STI) PCR Test

Understanding Sexually Transmitted Infections (STIs)

Sexually Transmitted Infections (STIs) are infections that spread through sexual contact and can affect the genital, anal, and oral areas. If left untreated, STIs can cause serious health complications, including infertility, chronic pain, and increased HIV risk.

The STI PCR Test is an advanced molecular diagnostic test that provides rapid and highly accurate detection of sexually transmitted infections using DNA/RNA amplification.

Why Choose the STI PCR Test?

Unlike traditional culture-based STI tests, the PCR (Polymerase Chain Reaction) test offers:
🔬 High Accuracy – Over 99% sensitivity and specificity
Fast Results – Detects infections in 24-48 hours
🦠 Multiple Infection Detection – Tests for multiple STIs in one sample
🚫 Early Detection – Identifies STIs before symptoms appear

Who Should Get an STI PCR Test?

You may need STI testing if you:
✅ Have had unprotected sex or a new sexual partner
✅ Are experiencing symptoms such as burning, discharge, or sores
✅ Have a partner diagnosed with an STI
✅ Are pregnant and need routine screening
✅ Engage in high-risk sexual behavior
✅ Want peace of mind about your sexual health

Symptoms of Common STIs

STI

Common Symptoms

Chlamydia

Burning sensation during urination, abnormal discharge

Gonorrhea

Painful urination, pelvic pain, discharge

Trichomoniasis

Itching, foul-smelling discharge, pain during sex

Mycoplasma Genitalium

Urethritis, vaginal discomfort, post-sex bleeding

Syphilis

Painless sores, rash, fever, swollen lymph nodes

Herpes (HSV-1, HSV-2)

Painful blisters or sores, itching

Human Papillomavirus (HPV)

Genital warts (some strains), cervical cancer risk

HIV

Flu-like symptoms, swollen glands, fatigue

What Infections Does the STI PCR Test Detect?

🔹 Bacterial STIs:

  • Chlamydia trachomatis
  • Neisseria gonorrhoeae (Gonorrhea)
  • Mycoplasma genitalium
  • Ureaplasma urealyticum
  • Treponema pallidum (Syphilis)
  • Haemophilus ducreyi (Chancroid)

🔹 Viral STIs:

  • Herpes Simplex Virus (HSV-1 & HSV-2)
  • Human Papillomavirus (HPV) (High-Risk Strains)
  • Hepatitis B Virus (HBV)
  • Hepatitis C Virus (HCV)
  • Human Immunodeficiency Virus (HIV-1 & HIV-2)

🔹 Parasitic STIs:

  • Trichomonas vaginalis

How is the STI PCR Test Performed?

1️⃣  Sample Collection – A urine sample, swab, or blood sample is collected depending on the infection being tested.
2️⃣  DNA/RNA Extraction – The sample is processed to extract genetic material from the pathogens.
3️⃣  PCR Amplification & Detection – The test amplifies the DNA/RNA of STIs for highly sensitive detection.
4️⃣  Results Interpretation – A detailed report is generated and sent to your doctor for review.

Why is PCR Testing Better Than Traditional STI Testing?

Feature

PCR Test

Traditional STI Testing

Detection Speed

24-48 hours

3-7 days

Accuracy

>99%

Lower sensitivity for some infections

Multiple Pathogen Detection

Yes

Limited

Early Detection

Yes

May require symptoms to appear

Understanding Your Test Results

  • Positive Result – Confirms the presence of an STI; treatment will be recommended by your doctor.
  • Negative Result – No infection detected, but regular screening is still advised.
  • Inconclusive Result – A retest may be needed if the sample was inadequate.

What Happens After Testing?

Your doctor will:
✔ Discuss your results in detail
✔ Prescribe antibiotics or antiviral medications if needed
✔ Provide treatment for you and your partner (if applicable)
✔ Recommend follow-up testing or additional screening

Insurance & Cost Coverage

Most insurance providers cover STI PCR testing if deemed medically necessary. We offer discreet billing options and can assist with insurance verification and financial assistance programs.

Why Choose Our Lab for STI PCR Testing?

Confidential & Discreet Testing – Private, secure, and HIPAA-compliant
Comprehensive STI Panels – Test for multiple infections in one sample
Fast Turnaround Time – Results available within 24-48 hours
High Sensitivity & AccuracyEarly and reliable detection
CLIA-Certified & CAP-Accredited Laboratory – Ensuring high-quality testing standards

Gastrointestinal Infection (PCR) Test

What is a Gastrointestinal Infection? 

A Gastrointestinal (GI) infection occurs when bacteria, viruses, or parasites infect the digestive tract, leading to diarrhea, nausea, vomiting, abdominal pain, and fever. These infections can be caused by contaminated food, water, person-to-person contact, or poor hygiene.

Traditional stool cultures can take several days to identify the cause, but the Gastrointestinal Infection PCR Test provides fast, accurate, and comprehensive detection of multiple pathogens within 24-48 hours using advanced molecular technology.

What is the Gastrointestinal Infection PCR Test? 

The Gastrointestinal Infection PCR Test is a molecular diagnostic test that detects bacteria, viruses, and parasites that cause GI illnesses. Unlike traditional tests that require longer processing times and may miss certain infections, PCR testing provides:
Highly Accurate Detection – Over 99% sensitivity and specificity
Rapid Results – Identifies infections within 24-48 hours instead of days or weeks
🦠 Simultaneous Multi-Pathogen Detection – Detects multiple infections in a single test
🚫 Detects Antibiotic Resistance Genes – Guides treatment by identifying drug-resistant infections

Who Should Get a Gastrointestinal Infection PCR Test? 

This test is recommended for individuals experiencing:
Severe or prolonged diarrhea (lasting more than 3 days)
Bloody diarrhea or mucus in stool
Severe abdominal pain, nausea, or vomiting
Fever, dehydration, or fatigue associated with GI symptoms
Recent travel to areas with poor sanitation or high infection risk
Immunocompromised conditions (HIV, cancer, or organ transplant patients)

Common Symptoms of GI Infections 

🛑 Frequent watery diarrhea
🛑 Abdominal cramps or pain
🛑 Fever and chills
🛑 Nausea and vomiting
🛑 Blood or mucus in stool
🛑 Severe dehydration (dry mouth, dizziness, low urine output)

What Pathogens Does the Gastrointestinal PCR Test Detect? 

Bacterial Pathogens: 

  • Clostridium difficile (C. diff toxin A/B) – Antibiotic-associated diarrhea
  • Salmonella species – Common foodborne infection
  • Shigella species – Causes severe dysentery
  • Escherichia coli (E. coli O157:H7, Enterotoxigenic E. coli, Shiga-toxin-producing E. coli) – Linked to food poisoning and traveler’s diarrhea
  • Campylobacter species – One of the most common causes of bacterial diarrhea
  • Vibrio species (including Vibrio cholerae) – Associated with cholera and seafood poisoning
  • Yersinia enterocolitica – Causes severe abdominal pain, mimicking appendicitis

Viral Pathogens:

  • Norovirus – The leading cause of viral gastroenteritis (“stomach flu”)
  • Rotavirus – Common in young children, causing severe diarrhea
  • Sapovirus – Another cause of viral gastroenteritis
  • Adenovirus (Enteric Type 40/41) – Causes prolonged diarrhea, especially in infants

Parasitic Pathogens:

  • Giardia lamblia – Causes Giardiasis, leading to prolonged diarrhea and bloating
  • Cryptosporidium species – Causes severe diarrhea in immunocompromised patients
  • Entamoeba histolytica – Causes Amoebiasis, leading to dysentery and liver abscesses

Antibiotic Resistance Genes Detected:

  • difficile toxin genes (TcdA, TcdB) – Indicates presence of Clostridium difficile infection
  • Beta-lactam resistance genes (blaCTX-M, blaNDM, blaOXA-48) – Indicates resistance to cephalosporins and carbapenems
  • Macrolide resistance genes (ermB) – Indicates resistance to macrolide antibiotics like azithromycin

How is the Gastrointestinal PCR Test Performed?

1️⃣  Sample Collection – A stool sample is collected in a sterile container at a lab or healthcare provider’s office.
2️⃣  DNA/RNA Extraction – The genetic material of pathogens is isolated.
3️⃣  PCR Amplification & Detection – The test amplifies the DNA/RNA of viruses, bacteria, and parasites.
4️⃣ Results Interpretation – A detailed report is generated and sent to your doctor for review.

Why is PCR Testing Better Than Traditional Stool Culture? 

Feature

PCR Test

Traditional Stool Culture

Speed

24-48 hours

3-7 days

Accuracy

>99%

Lower sensitivity

Multiple Pathogen Detection

Yes

No

Antibiotic Resistance Detection

Yes

No

Early Detection

Yes

May require symptoms to appear

Understanding Your Test Results 

  • Positive Result – Confirms the presence of one or more pathogens; your doctor will provide appropriate treatment.
  • Negative Result – No infection detected, but symptoms should still be monitored.
  • Antibiotic Resistance Detected – Your doctor will adjust antibiotic therapy

What Happens After Testing? 

Depending on your results, your doctor may:
Prescribe targeted antibiotics, antivirals, or antiparasitic medications
Recommend hydration therapy and probiotics for gut recovery
Advise dietary changes and hygiene practices to prevent reinfection
Suggest further testing if symptoms persist

Insurance & Cost Coverage 

Most insurance providers cover PCR testing for gastrointestinal infections when medically necessary. Our team assists with insurance verification, pre-authorization, and billing support.

Why Choose Our Lab for Gastrointestinal PCR Testing? 

Comprehensive Multi-Pathogen Panel – Detects bacteria, viruses, and parasites in one test
CLIA-Certified & CAP-Accredited Laboratory – Ensuring high-quality diagnostic standards
Fast Turnaround Time – Results available within 24-48 hours
Expert Consultation Available – Helping physicians interpret complex infection cases
Advanced Molecular Technology – Utilizes state-of-the-art PCR testing for accurate detection

What is a Nail Infection?

Nail infections, also known as onychomycosis, occur when fungi, bacteria, or yeast infect the fingernails or toenails. These infections can cause discoloration, thickening, brittleness, pain, and nail detachment. Traditional lab cultures for diagnosing nail infections can take weeks and often fail to detect slow-growing pathogens.

The Nail Infection PCR Test provides a fast, accurate, and comprehensive diagnosis using Polymerase Chain Reaction (PCR) technology, detecting fungal, bacterial, and viral infections within 24-48 hours.

Why Choose the PCR Test for Nail Infections?

Unlike conventional microscopy or culture tests, which may miss certain pathogens, the PCR test directly detects DNA/RNA of infecting organisms, providing:
High Accuracy – Detects infections with >99% sensitivity and specificity
Rapid Results – Identifies pathogens in 24-48 hours instead of waiting weeks for culture growth
🦠 Multi-Pathogen Detection – Identifies fungi, bacteria, and viruses in a single test
🚫 Detects Antibiotic & Antifungal Resistance – Helps guide targeted treatment

Who Should Get a Nail Infection PCR Test?

You may need PCR testing for nail infections if you have:
Thickened, discolored, or brittle nails
Nail lifting, crumbling, or deformity
Persistent nail infections that do not respond to treatment
Diabetes or an immune condition that increases infection risk
Recurrent nail infections

Symptoms of Nail Infections

🛑 Yellow, brown, or white discoloration
🛑 Thickened or distorted nail shape
🛑 Brittle, crumbling nails
🛑 Separation of the nail from the nail bed
🛑 Pain or foul odor around the nail

What Pathogens Does the Nail Infection PCR Test Detect?

Fungal Nail Infections (Onychomycosis):

  • Dermatophytes (Most common cause of fungal nail infections)
    • Trichophyton rubrum
    • Trichophyton mentagrophytes
    • Epidermophyton floccosum
  • Non-Dermatophyte Fungi
    • Aspergillus species (Mold-related infections)
    • Scopulariopsis brevicaulis (Hard-to-treat fungal nail infections)
  • Yeast Infections
    • Candida albicans (Common in diabetics and immunocompromised individuals)
    • Candida parapsilosis

Bacterial Nail Infections:

  • Pseudomonas aeruginosa (Green nail syndrome)
  • Staphylococcus aureus (Bacterial paronychia)
  • Streptococcus species

Viral Nail Infections:

  • Human Papillomavirus (HPV) – Associated with periungual warts
  • Herpes Simplex Virus (HSV-1 & HSV-2) – Can cause painful nail lesions

Antifungal & Antibiotic Resistance Genes Detected:

  • Azole Resistance (CYP51A mutations) – Resistance to common antifungal treatments
  • Beta-lactam & Methicillin Resistance (mecA gene) – Indicates MRSA presence in bacterial infections

How is the Nail Infection PCR Test Performed?

1️⃣ Sample Collection – A small nail clipping or debris sample is taken from the affected nail.
2️⃣ DNA/RNA Extraction – The sample is processed to extract genetic material from pathogens.
3️⃣ PCR Amplification & Analysis – The genetic material is amplified for highly sensitive detection.
4️⃣ Results Interpretation – A report is generated and sent to your doctor for precise treatment planning.

Why is PCR Testing Better Than Traditional Culture?

Feature

PCR Test

Traditional Culture

Speed

24-48 hours

2-6 weeks

Accuracy

>99%

May miss slow-growing fungi

Multiple Pathogen Detection

Yes

No

Antibiotic & Antifungal Resistance Detection

Yes

No

Understanding Your Test Results

🔹 Positive Result – Confirms a fungal, bacterial, or viral infection; your doctor will prescribe targeted treatment.
🔹 Negative Result – No infection detected, but symptoms should still be monitored.
🔹 Resistance Detected – Your doctor will adjust antifungal or antibiotic therapy accordingly.

What Happens After Testing?

Targeted Treatment – Your doctor will prescribe an oral or topical antifungal, antibiotic, or antiviral treatment based on your results.
Proper Nail Care – Regular trimming, keeping nails dry, and antifungal treatments can help prevent reinfection.
Follow-Up Testing – If symptoms persist, retesting may be necessary to monitor treatment success.

Insurance & Cost Coverage

Most insurance providers cover PCR testing for nail infections when medically necessary. Our team assists with insurance verification and billing support.

Why Choose Our Lab for Nail Infection PCR Testing?

Comprehensive Pathogen Screening – Detects fungi, bacteria, and viruses in one test
CLIA-Certified & CAP-Accredited Lab – Ensuring high-quality diagnostic standards
Fast Turnaround Time – Results available within 24-48 hours
Advanced Molecular Technology – Uses state-of-the-art PCR testing for precision

Respiratory Pathogens Panel (RRP) - PCR Test

What is the Respiratory Pathogens Panel (RRP) – PCR Test? 

The Respiratory Pathogens Panel (RRP) PCR Test is an advanced molecular diagnostic test designed to detect multiple bacterial, viral, and fungal infections that cause respiratory illnesses. This highly accurate test utilizes Polymerase Chain Reaction (PCR) technology to quickly identify respiratory pathogens, allowing for rapid diagnosis and targeted treatment.

Why is the RRP PCR Test Important?

Respiratory infections can be caused by a variety of viruses, bacteria, and fungi, many of which have overlapping symptoms. The RRP PCR test provides fast and precise identification of the pathogen, helping doctors determine:
✅ The exact cause of respiratory symptoms
✅ Whether antibiotics are needed (bacterial vs. viral infection)
✅ If a patient has a single or multiple infections
✅ The appropriate treatment based on pathogen detection

Who Should Get the RRP PCR Test?

This test is recommended for individuals experiencing:
Cough, fever, difficulty breathing, or chest tightness
Severe flu-like symptoms that are persistent or worsening
High-risk conditions (elderly, immunocompromised, or those with chronic lung diseases)
Exposure to someone with a known respiratory infection
Recurring or long-lasting respiratory infections

What Infections Does the RRP PCR Test Detect?

Viral Pathogens:

  • Influenza A & B (Flu Virus)
  • SARS-CoV-2 (COVID-19 Virus)
  • Respiratory Syncytial Virus (RSV A & B)
  • Human Rhinovirus/Enterovirus (Common Cold Viruses)
  • Human Metapneumovirus (hMPV)
  • Parainfluenza Virus (Types 1, 2, 3, 4)
  • Adenovirus (Common in Respiratory Infections)
  • Coronavirus Strains (229E, NL63, OC43, HKU1)

Bacterial Pathogens:

  • Mycoplasma pneumoniae (Atypical Pneumonia)
  • Chlamydia pneumoniae (Walking Pneumonia)
  • Bordetella pertussis (Whooping Cough)
  • Bordetella parapertussis (Mild Whooping Cough Variant)
  • Haemophilus influenzae (Secondary Bacterial Infection Post-Flu)
  • Streptococcus pneumoniae (Pneumococcal Pneumonia)
  • Legionella pneumophila (Legionnaires’ Disease)

Fungal Pathogens (if included in testing panel): 

  • Aspergillus species (Fungal Pneumonia in Immunocompromised Patients)
  • Pneumocystis jirovecii (Pneumocystis Pneumonia – PCP, Common in HIV Patients)

How is the RRP PCR Test Performed? 

1️⃣ Sample Collection – A nasopharyngeal swab, throat swab, or sputum sample is collected.
2️⃣ DNA/RNA Extraction – The genetic material of pathogens is isolated from the sample.
3️⃣ PCR Amplification & Analysis – The test amplifies and detects the genetic material of viruses, bacteria, and fungi.
4️⃣ Results Interpretation – A detailed report is generated and provided to your physician.

Benefits of the RRP PCR Test 

Fast & Accurate Diagnosis – Provides results within 24-48 hours
Simultaneous Multi-Pathogen Detection – Identifies multiple infections in one test
Reduces Unnecessary Antibiotic Use – Helps determine bacterial vs. viral infection
Improved Treatment Decisions – Guides doctors in choosing the right medication
Essential for High-Risk Individuals – Early detection prevents serious complications

How Does PCR Compare to Traditional Testing?

Feature

PCR Test

Traditional Culture or Rapid Tests

Speed

24-48 hours

3-7 days (culture testing)

Accuracy

>99%

Lower sensitivity

Multiple Pathogen Detection

Yes

No

Antibiotic Resistance Detection

In some panels

No

Interpreting Your Test Results

  • Positive Result – Confirms the presence of a respiratory pathogen. Your doctor will provide appropriate treatment.
  • Negative Result – No infection detected, but symptoms should still be monitored.
  • Multiple Pathogens Detected – More than one infection is present, requiring specialized treatment.

What Happens After Testing? 

Depending on your results, your doctor may:
Prescribe antivirals or antibiotics based on pathogen detection
Recommend supportive care (hydration, rest, oxygen therapy)
Suggest quarantine or infection prevention measures
Perform additional testing for complications such as pneumonia

Insurance & Cost Coverage 

Most insurance providers cover RRP PCR testing for individuals with symptoms or high-risk conditions. Our team assists with insurance verification, pre-authorization, and financial options.

Why Choose Our Lab for RRP PCR Testing? 

Comprehensive Multi-Pathogen Panel – Detects over 20+ respiratory infections
CLIA-Certified & CAP-Accredited Laboratory – Ensuring high-quality diagnostic standards
Fast Turnaround Time – Results available within 24-48 hours
Expert Consultation Available – Helps doctors and patients interpret results
Advanced Molecular Technology – Utilizes state-of-the-art PCR testing for accuracy

What is a Wound Care PCR Test? 

A Wound Care PCR (Polymerase Chain Reaction) Test is an advanced molecular diagnostic test that rapidly identifies bacteria, viruses, fungi, and antibiotic resistance genes present in infected wounds. Unlike traditional culture-based methods, PCR testing offers fast and accurate results within 24-48 hours, allowing for targeted treatment and better wound healing outcomes.

Why is PCR Testing Important for Wound Infections?

Wound infections can delay healing, increase the risk of complications, and lead to serious conditions such as cellulitis, sepsis, or osteomyelitis (bone infection). The Wound Care PCR Test helps identify the exact pathogens causing infection and detects antibiotic resistance genes, allowing for precise and effective treatment.

Key Benefits of Wound Care PCR Testing

Rapid Detection – Results within 24-48 hours, compared to 3-5 days for culture testing
High Sensitivity & Accuracy – Identifies hard-to-grow bacteria, fungi, and viruses
Detects Polymicrobial Infections – Finds multiple pathogens in chronic and non-healing wounds
Guides Targeted Treatment – Reduces unnecessary antibiotic use by detecting antibiotic-resistant genes
Minimally Invasive Testing – Requires only a swab or tissue sample

Who Should Get a Wound Care PCR Test?

This test is recommended for patients with:
Chronic or non-healing wounds (lasting more than 2-4 weeks)
Diabetic foot ulcers or pressure sores with signs of infection
Surgical wounds that are not healing properly
Burn wounds showing infection symptoms
Trauma wounds with redness, swelling, or pus formation
Infected wounds in immunocompromised individuals

Common Signs of Wound Infection

🛑 Increased redness, swelling, or warmth around the wound
🛑 Pain that worsens instead of improving
🛑 Pus or foul-smelling drainage
🛑 Slow or stalled wound healing
🛑 Fever, chills, or fatigue (signs of systemic infection)

What Pathogens Does the Wound Care PCR Test Detect? 

Bacterial Infections:

  • Staphylococcus aureus (including MRSA) – Common in skin and wound infections
  • Pseudomonas aeruginosa – Frequently found in burn wounds and chronic ulcers
  • Streptococcus pyogenes (Group A Strep) – Causes severe soft tissue infections
  • Enterococcus species (VRE) – Common in hospital-acquired infections
  • Klebsiella pneumoniae – Found in surgical site infections
  • Escherichia coli (E. coli) – Can cause complicated wound infections

Fungal Pathogens:

  • Candida species – Can delay wound healing and cause fungal infections
  • Aspergillus species – A risk in immunocompromised patients

Viral Pathogens:

  • Herpes Simplex Virus (HSV-1, HSV-2) – Can cause painful skin ulcers
  • Varicella-Zoster Virus (VZV) – Linked to shingles-related skin infections

Antibiotic Resistance Genes Detected: 

  • Methicillin-resistant Staphylococcus aureus (MRSA)
  • Vancomycin-resistant Enterococcus (VRE)
  • Extended-Spectrum Beta-Lactamases (ESBLs) – Resistance to penicillin and cephalosporins
  • Carbapenem-resistant Enterobacteriaceae (CRE) – Resistance to powerful antibiotics

How is the Wound Care PCR Test Performed? 

1️⃣  Sample Collection – A swab or tissue sample is taken from the wound site.
2️⃣  DNA/RNA Extraction – The sample is processed to extract microbial genetic material.
3️⃣  PCR Amplification & Analysis – The genetic material is amplified to detect bacterial, viral, and fungal infections.
4️⃣  Results Interpretation – A detailed report is provided to the physician for targeted treatment.

PCR vs. Traditional Wound Culture – Why Choose PCR? 

Feature

PCR Test

Traditional Wound Culture

Speed

24-48 hours

3-7 days

Accuracy

>99%

Lower sensitivity

Multiple Pathogen Detection

Yes

May miss some organisms

Antibiotic Resistance Detection

Yes

No

Growth Required for Detection

No

Yes (may miss slow-growing bacteria)

Understanding Your Test Results 

🔹 Positive Result – Confirms the presence of bacteria, fungi, or viruses; your doctor will prescribe the appropriate treatment.
🔹 Negative Result – No infection detected, but symptoms should still be monitored.
🔹 Antibiotic Resistance Detected – Your doctor will adjust your antibiotic therapy accordingly.

What Happens After Testing?

 Based on your results, your doctor may:
Prescribe targeted antibiotics or antifungal medication
Recommend wound debridement or specialized wound care
Suggest lifestyle modifications for better healing
Refer you to a specialist for chronic wound management

Insurance & Cost Coverage

Most insurance providers cover PCR testing for wound infections when medically necessary. Our team can assist with insurance verification, pre-authorization, and billing support.

Why Choose Our Lab for Wound Care PCR Testing? 

Comprehensive Pathogen Detection – Identifies bacteria, fungi, and viruses in one test
CLIA-Certified & CAP-Accredited Lab – Ensuring high-quality diagnostic standards
Fast Turnaround Time – Results available within 24-48 hours
Expert Consultation Available – Helping physicians interpret complex infection cases
Advanced Molecular Technology – Using state-of-the-art PCR testing for accurate detection

Why Choose Medex Laboratories Inc.?

Conclusion

Medex Laboratories Inc. provides advanced PCR-based testing for respiratory infections, urinary tract infections (UTIs), and sexually transmitted infections (STIs). These tests offer:
• High sensitivity and specificity for accurate diagnosis.
• Detection of multiple pathogens in a single test panel for efficient screening.
• Antibiotic resistance profiling to guide appropriate treatment decisions.